VC  Pappas Ventures

     Office Locations:

2520 Meridian Parkway, Suite 400
Durham, NC 27713

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  • Early
  • Expansion
  • Growth
  • Seed



  • Life Sciences & Healthcare
  • Medical Device



    Pappas Ventures is a life sciences venture capital firm located in the Research Triangle area of North Carolina. Since 1994 the firm has been investing in and nurturing promising young companies. Pappas has $353 million in capital under management and has invested in more than 50 portfolio companies throughout the United States. The firm invests exclusively in the life sciences sector: biotechnology, biopharmaceuticals, specialty pharmaceuticals, drug delivery, and medical devices. Pappas Ventures invests a substantial portion (about half) of its capital in early-stage companies that have yet to begin testing their products in clinical trials. Pappas invests the other half in companies whose lead products are at the Phase 1 or Phase 2 stage of development. Investment size ranges from $100,000 in a seed deal to as much as $6 million in a later-stage mezzanine transaction.

    Investment Firm Key

       VC = Venture Capital
       PE = Private Equity
       A = Angel
       I = Incubator
       MB = Merchant Bank
       VD = Venture Debt
       FI = Family Investment Office
       FOF = Fund of Funds
       ED = Economic Development Office   
       TT = Technology Transfer Office
       CVC = Corporate Venture Capital
       SEC = Secondary Purchaser
       HF = Hedge Fund/Mutual Fund
    Venture Capital
    Seed Stage
    (includes "pre-seed," or
    concept stage)
    No Revenue
    Early StageMinimal
    Growth Stage
    (also called Mid-stage)
    Expansion Stage
    (also called Late-stage)
    $7M and greater
    Private Equity
    Lower Middle Market$10M-$249M
    Middle Market$250M-$499M
    Upper Middle Market$500M-$1B
    Large Cap>$1B

    Investment Team:

    Name   Title
    Get the complete investment team + individual email addresses for investment team partners. Get personal images, LinkedIn links, investment specialties, office locations and more with a National Database subscription.
    Arthur M. Pappas Managing Partner
    Ernie Mario PhD Venture Partner
    Ford S. Worthy JD Partner
    Franz Humer Venture Partner & Senior Advisor
    Kyle Rasbach PhD, PharmD Partner


    Recent Funding Events (trailing 12 months):










      Series A


    Portfolio companies include:

      Achillion Pharmaceuticals
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      Afferent Pharmaceuticals
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      Amplyx Pharmaceuticals
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      Anthera Pharmaceuticals
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      Balance Therapeutics
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      Bayhill Therapeutics
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      CeNeRx BioPharma
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      Colucid Pharmaceuticals
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      Evidation Health
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      IlluminOss Medical
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      IlluminOsss Medical
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      Liquidia Technologies
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      Lumena Pharmaceuticals
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      Marina Biotech
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      Milestone Pharmaceuticals
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      Sensys Medical
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      Syndax Pharmaceuticals
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      Thrasos Therapeutics
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      UltraGenyx Pharmaceutical
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    Recent News:

      There is no recent news for Pappas Ventures.